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Issue Highlights page A19 Full Text | Full-Text PDF (31 KB)
Editorials
What Is Your Patient's GPA and Why Does It Matter? Managing Brain Metastases and the Cost of Hope Paul W. Sperduto pages 643-644 Full Text | Full-Text PDF (57 KB)
Adjuvant Pancreatic Cancer Therapy: No One Should Go It Alone or Be Left Behind Joseph M. Herman, William F. Regine pages 645-647 Full Text | Full-Text PDF (66 KB)
Clinical Investigations
Brain
Randomized Comparison of Whole Brain Radiotherapy, 20 Gy in Four Daily Fractions Versus 40 Gy in 20 Twice-Daily Fractions, for Brain Metastases, 15 October 2009 P.H. Graham, J. Bucci, L. Browne pages 648-654 Abstract | Full Text | Full-Text PDF (162 KB)
Diagnosis-Specific Prognostic Factors, Indexes, and Treatment Outcomes for Patients With Newly Diagnosed Brain Metastases: A Multi-Institutional Analysis of 4,259 Patients, 25 November 2009 Paul W. Sperduto, Samuel T. Chao, Penny K. Sneed, Xianghua Luo, John Suh, David Roberge, Amit Bhatt, Ashley W. Jensen, Paul D. Brown, Helen Shih, John Kirkpatrick, Amanda Schwer, Laurie E. Gaspar, John B. Fiveash, Veronica Chiang, Jonathan Knisely, Christina Maria Sperduto, Minesh Mehta pages 655-661 Abstract | Full Text | Full-Text PDF (109 KB)
Cognition and Quality of Life After Chemotherapy Plus Radiotherapy (RT) vs. RT for Pure and Mixed Anaplastic Oligodendrogliomas: Radiation Therapy Oncology Group Trial 9402, 23 September 2009 Meihua Wang, Gregory Cairncross, Edward Shaw, Robert Jenkins, Bernd Scheithauer, David Brachman, Jan Buckner, Karen Fink, Luis Souhami, Normand Laperriere, Minesh Mehta, Walter Curran, Radiation Therapy Oncology Group (RTOG), North Central Cancer Treatment Group (NCCTG), Southwest Oncology Group (SWOG), National Cancer Institute of Canada Clinical Trials Group (NCIC CTG), Eastern Cooperative Oncology Group (ECOG) pages 662-669 Abstract | Full Text | Full-Text PDF (458 KB)
Chemoradiotherapy of Newly Diagnosed Glioblastoma With Intensified Temozolomide, 15 October 2009 Markus Weiler, Christian Hartmann, Dorothee Wiewrodt, Ulrich Herrlinger, Thierry Gorlia, Oliver Bähr, Richard Meyermann, Michael Bamberg, Marcos Tatagiba, Andreas von Deimling, Michael Weller, Wolfgang Wick pages 670-676 Abstract | Full Text | Full-Text PDF (140 KB)
Skin
Effect of Radiotherapy Dose and Volume on Relapse in Merkel Cell Cancer of the Skin, 10 November 2009 Matthew Foote, Jennifer Harvey, Sandro Porceddu, Graeme Dickie, Susan Hewitt, Shoni Colquist, Dannie Zarate, Michael Poulsen pages 677-684 Abstract | Full Text | Full-Text PDF (500 KB)
Lung
Early Graphical Appearance of Radiation Pneumonitis Correlates With the Severity of Radiation Pneumonitis After Stereotactic Body Radiotherapy (SBRT) in Patients With Lung Tumors Atsuya Takeda, Toshio Ohashi, Etsuo Kunieda, Tatsuji Enomoto, Naoko Sanuki, Toshiaki Takeda, Naoyuki Shigematsu pages 685-690 Abstract | Full Text | Full-Text PDF (157 KB)
Impact of Toxicity Grade and Scoring System on the Relationship Between Mean Lung Dose and Risk of Radiation Pneumonitis in a Large Cohort of Patients With Non–Small Cell Lung Cancer, 15 October 2009 Susan L. Tucker, Hekun Jin, Xiong Wei, Shulian Wang, Mary K. Martel, Ritsuko Komaki, H. Helen Liu, Radhe Mohan, Yuhchyau Chen, James D. Cox, Zhongxing Liao pages 691-698 Abstract | Full Text | Full-Text PDF (379 KB)
PET CT Thresholds for Radiotherapy Target Definition in Non–Small-Cell Lung Cancer: How Close Are We to the Pathologic Findings?, 15 October 2009 Kailiang Wu, Yee C. Ung, Jennifer Hornby, Marc Freeman, David Hwang, Ming S. Tsao, Max Dahele, Gail Darling, Donna E. Maziak, Romeo Tirona, Kathy Mah, C. Shun Wong pages 699-706 Abstract | Full Text | Full-Text PDF (678 KB)
Head and Neck
Dosimetric Evaluation of Automatic Segmentation for Adaptive IMRT for Head-and-Neck Cancer, 15 March 2010 Stuart Y. Tsuji, Andrew Hwang, Vivian Weinberg, Sue S. Yom, Jeanne M. Quivey, Ping Xia pages 707-714 Abstract | Full Text | Full-Text PDF (1104 KB)
Concurrent Chemoradiotherapy With Helical Tomotherapy for Oropharyngeal Cancer: A Preliminary Result, 29 October 2009 Pei-Wei Shueng, Le-Jung Wu, Shiou-Yi Chen, Chi-Huang Hsiao, Hui-Ju Tien, Po-Wen Cheng, Ying-Shiung Kuo, Yu-Jen Chen, Chien-An Chen, Pei-Ying Hsieh, Chen-Hsi Hsieh pages 715-721 Abstract | Full Text | Full-Text PDF (256 KB)
Cognitive Function Before and After Intensity-Modulated Radiation Therapy in Patients With Nasopharyngeal Carcinoma: A Prospective Study, 30 December 2009 Kuan-Yin Hsiao, Shyh-An Yeh, Chiung-Chih Chang, Pei-Chien Tsai, Jia-Ming Wu, Jhy-Shyan Gau pages 722-726 Abstract | Full Text | Full-Text PDF (102 KB)
Evaluating and Reporting Dysphagia in Trials of Chemoirradiation for Head-and-Neck Cancer, 23 September 2009 Iris Gluck, Felix Y. Feng, Teresa Lyden, Marc Haxer, Francis Worden, Douglas B. Chepeha, Avraham Eisbruch pages 727-733 Abstract | Full Text | Full-Text PDF (204 KB)
Pancreas
Intraoperative Radiotherapy for Resected Pancreatic Cancer: A Multi-Institutional Retrospective Analysis of 210 Patients, 08 March 2010 Kazuhiko Ogawa, Katsuyuki Karasawa, Yoshinori Ito, Yoshihiro Ogawa, Keiichi Jingu, Hiroshi Onishi, Shinichi Aoki, Hitoshi Wada, Masaki Kokubo, Hidehiro Etoh, Tomoko Kazumoto, Makoto Takayama, Yoshiharu Negoro, Kenji Nemoto, Yasumasa Nishimura, JROSG Working Subgroup of Gastrointestinal Cancers pages 734-742 Abstract | Full Text | Full-Text PDF (250 KB)
Patterns of Radiotherapy Practice for Pancreatic Cancer in Japan: Results of the Japanese Radiation Oncology Study Group (JROSG) Survey, 29 October 2009 Kazuhiko Ogawa, Yoshinori Ito, Katsuyuki Karasawa, Yoshihiro Ogawa, Hiroshi Onishi, Tomoko Kazumoto, Keiko Shibuya, Hitoshi Shibuya, Yoshishige Okuno, Shigeo Nishino, Etsuyo Ogo, Nobue Uchida, Kumiko Karasawa, Kenji Nemoto, Yasumasa Nishimura, JROSG Working Subgroup of Gastrointestinal Cancers pages 743-750 Abstract | Full Text | Full-Text PDF (413 KB)
Cervix
Multi-Institutional Phase II Clinical Study of Concurrent Chemoradiotherapy for Locally Advanced Cervical Cancer in East and Southeast Asia, 15 October 2009 Shingo Kato, Tatsuya Ohno, Kullathorn Thephamongkhol, Yaowalak Chansilpa, Yang Yuxing, C.R. Beena Devi, Anita Z. Bustam, Miriam J.C. Calaguas, Rey H. de los Reyes, Chul-Koo Cho, To Anh Dung, Nana Supriana, Hideyuki Mizuno, Takashi Nakano, Hirohiko Tsujii pages 751-757 Abstract | Full Text | Full-Text PDF (125 KB)
Rectal Dose and Source Strength of the High-Dose-Rate Iridium-192 Both Affect Late Rectal Bleeding After Intracavitary Radiation Therapy for Uterine Cervical Carcinoma, 15 October 2009 Fumiaki Isohashi, Yasuo Yoshioka, Masahiko Koizumi, Osamu Suzuki, Koji Konishi, Iori Sumida, Yutaka Takahashi, Toshiyuki Ogata, Tadayuki Kotsuma, Takehiro Inoue pages 758-764 Abstract | Full Text | Full-Text PDF (208 KB)
A Dose–Volume Analysis of Magnetic Resonance Imaging-Aided High-Dose-Rate Image-Based Interstitial Brachytherapy for Uterine Cervical Cancer, 15 October 2009 Ken Yoshida, Hideya Yamazaki, Tadashi Takenaka, Tadayuki Kotsuma, Mineo Yoshida, Seiichi Furuya, Eiichi Tanaka, Tadaaki Uegaki, Keiko Kuriyama, Hisanobu Matsumoto, Shigetoshi Yamada, Chiaki Ban pages 765-772 Abstract | Full Text | Full-Text PDF (812 KB)
Prostate
Late Gastrointestinal Toxicity After Dose-Escalated Conformal Radiotherapy for Early Prostate Cancer: Results From the UK Medical Research Council RT01 Trial (ISRCTN47772397), 15 October 2009 Isabel Syndikus, Rachel C. Morgan, Matthew R. Sydes, John D. Graham, David P. Dearnaley, MRC RT01 collaborators pages 773-783 Abstract | Full Text | Full-Text PDF (389 KB) | Add-Ons
Unilateral Prostate Cancer Cannot be Accurately Predicted in Low-Risk Patients, 27 October 2009 Hendrik Isbarn, Pierre I. Karakiewicz, Susanne Vogel, Claudio Jeldres, Giovanni Lughezzani, Alberto Briganti, Francesco Montorsi, Paul Perrotte, Sascha A. Ahyai, Lars Budäus, Christian Eichelberg, Roman Heuer, Jens Köllermann, Guido Sauter, Thorsten Schlomm, Thomas Steuber, Alexander Haese, Mario Zacharias, Margit Fisch, Hans Heinzer, Hartwig Huland, Felix K.H. Chun, Markus Graefen pages 784-787 Abstract | Full Text | Full-Text PDF (90 KB)
External Validation of a Preoperative Nomogram for Prediction of the Risk of Recurrence After Radical Prostatectomy, 09 October 2009 Hendrik Isbarn, Pierre I. Karakiewicz, Jochen Walz, Sascha A. Ahyai, Thomas Steuber, Alexander Haese, Lars Budäus, Thorsten Schlomm, Christian Eichelberg, Roman Heuer, Hans Heinzer, Hartwig Huland, Markus Graefen, Felix K.H. Chun pages 788-792 Abstract | Full Text | Full-Text PDF (361 KB)
Validation of the Intestinal Part of the Prostate Cancer Questionnaire “QUFW94”: Psychometric Properties, Responsiveness, and Content Validity, 29 October 2009 Randi J. Reidunsdatter, Jo-Åsmund Lund, Per Fransson, Anders Widmark, Sophie D. Fosså, Stein Kaasa pages 793-804 Abstract | Full Text | Full-Text PDF (172 KB)
Hypofractionated Radiotherapy for Favorable Risk Prostate Cancer Nicholas Rene, Sergio Faria, Fabio Cury, Marc David, Marie Duclos, George Shenouda, Luis Souhami pages 805-810 Abstract | Full Text | Full-Text PDF (117 KB)
Single-Fraction High-Dose-Rate Brachytherapy and Hypofractionated External Beam Radiotherapy for Men With Intermediate-Risk Prostate Cancer: Analysis of Short- and Medium-Term Toxicity and Quality of Life, 15 October 2009 Gerard C. Morton, D. Andrew Loblaw, Raxa Sankreacha, Andrea Deabreu, Liying Zhang, Alexandre Mamedov, Patrick Cheung, Brian Keller, Cyril Danjoux, Ewa Szumacher, Gillian Thomas pages 811-817 Abstract | Full Text | Full-Text PDF (259 KB)
Insufficiency Fractures After Pelvic Radiotherapy in Patients With Prostate Cancer, 29 October 2009 Şefik İğdem, Gül Alço, Tülay Ercan, Metin Barlan, Kürşat Ganiyusufoğlu, Bülent Ünalan, Sedat Turkan, Sait Okkan pages 818-823 Abstract | Full Text | Full-Text PDF (403 KB)
Cross-Linked Hyaluronan Gel Reduces the Acute Rectal Toxicity of Radiotherapy for Prostate Cancer Richard B. Wilder, Greg A. Barme, Ronald F. Gilbert, Richard E. Holevas, Luis I. Kobashi, Richard R. Reed, Ronald S. Solomon, Nancy L. Walter, Lucy Chittenden, Albert V. Mesa, Jeffrey Agustin, Jessica Lizarde, Jorge Macedo, John Ravera, Kenneth M. Tokita pages 824-830 Abstract | Full Text | Full-Text PDF (688 KB)
Breast
Variation in Post-Surgical Lumpectomy Cavity Volume With Delay in Initiation of Breast Irradiation Because of Chemotherapy, 01 October 2009 Jonathan B. Strauss, Benjamin T. Gielda, Sea S. Chen, Anand P. Shah, Ross A. Abrams, Katherine L. Griem pages 831-835 Abstract | Full Text | Full-Text PDF (201 KB)
Feasibility of Postmastectomy Treatment With Helical TomoTherapy, 30 October 2009 Michael Ashenafi, Robert A. Boyd, Tae K. Lee, Kenneth K. Lo, John P. Gibbons, Isaac I. Rosen, Jonas D. Fontenot, Kenneth R. Hogstrom pages 836-842 Abstract | Full Text | Full-Text PDF (690 KB)
Sarcoma
An Effective Preoperative Three-Dimensional Radiotherapy Target Volume for Extremity Soft Tissue Sarcoma and the Effect of Margin Width on Local Control, 14 December 2009 BoKyong Kim, Yen-Lin E. Chen, David G. Kirsch, Saveli I. Goldberg, Wendy Kobayashi, Jong Hyun Kung, John A. Wolfgang, Karen Doppke, Andrew E. Rosenberg, G. Petur Nielsen, Kevin A. Raskin, Dempsey S. Springfield, Joseph H. Schwab, Mark C. Gebhardt, Sam S. Yoon, Francis J. Hornicek, Thomas F. DeLaney pages 843-850 Abstract | Full Text | Full-Text PDF (246 KB)
Normal Tissue
Computed Tomography Perfusion Assessment of Radiation Therapy Effects on Spinal Cord Hemodynamics, 16 December 2009 Maria Vittoria Spampinato, Sotirios Bisdas, Anand K. Sharma, Daniel McDonald, Primož Strojan, Zoran Rumboldt pages 851-857 Abstract | Full Text | Full-Text PDF (556 KB)
Biology Contributions
Differential Gene Expression Profiles of Radioresistant Non–Small-Cell Lung Cancer Cell Lines Established by Fractionated Irradiation: Tumor Protein p53-Inducible Protein 3 Confers Sensitivity to Ionizing Radiation Young Sook Lee, Jung-Hwa Oh, Seokjoo Yoon, Myung-Sang Kwon, Chang-Woo Song, Ki-Hwan Kim, Moon-June Cho, Mohamad Lalmodin Mollah, Young Jin Je, Yoon-Dong Kim, Chang Deok Kim, Jeung-Hoon Lee pages 858-866 Abstract | Full Text | Full-Text PDF (743 KB) | Add-Ons
Plasma Proteomic Analysis May Identify New Markers for Radiation-Induced Lung Toxicity in Patients With Non–Small-Cell Lung Cancer Xu-Wei Cai, Kerby Shedden, Xiaoping Ao, Mary Davis, Xiao-Long Fu, Theodore S. Lawrence, David M. Lubman, Feng-Ming (Spring) Kong pages 867-876 Abstract | Full Text | Full-Text PDF (1264 KB)
Response to Multiple Radiation Doses of Human Colorectal Carcinoma Cells Infected With Recombinant Adenovirus Containing Dominant-Negative Ku70 Fragment Muneyasu Urano, Fuqiu He, Akiko Minami, C. Clifton Ling, Gloria C. Li pages 877-885 Abstract | Full Text | Full-Text PDF (621 KB)
Tumor Cell Response to Synchrotron Microbeam Radiation Therapy Differs Markedly From Cells in Normal Tissues Jeffrey C. Crosbie, Robin L. Anderson, Kai Rothkamm, Christina M. Restall, Leonie Cann, Saleela Ruwanpura, Sarah Meachem, Naoto Yagi, Imants Svalbe, Robert A. Lewis, Bryan R.G. Williams, Peter A.W. Rogers pages 886-894 Abstract | Full Text | Full-Text PDF (1886 KB) | Add-Ons
High Dose–Per-Fraction Irradiation of Limited Lung Volumes Using an Image-Guided, Highly Focused Irradiator: Simulating Stereotactic Body Radiotherapy Regimens in a Small-Animal Model Jaeho Cho, Reinhard Kodym, Serguei Seliounine, James A. Richardson, Timothy D. Solberg, Michael D. Story pages 895-902 Abstract | Full Text | Full-Text PDF (2206 KB)
Red Shell: Defining a High-Risk Zone of Normal Tissue Damage in Stereotactic Body Radiation Therapy, 19 April 2010 Jun Yang, Jack F. Fowler, John P. Lamond, Rachelle Lanciano, Jing Feng, Luther W. Brady pages 903-909 Abstract | Full Text | Full-Text PDF (800 KB) | Add-Ons
Physics Contributions
Anatomic and Pathologic Variability During Radiotherapy for a Hybrid Active Breath-Hold Gating Technique Carri K. Glide-Hurst, Ellen Gopan, Geoffrey D. Hugo pages 910-917 Abstract | Full Text | Full-Text PDF (607 KB)
Interfraction and Intrafraction Changes in Amplitude of Breathing Motion in Stereotactic Liver Radiotherapy, 08 March 2010 Robert B. Case, Douglas J. Moseley, Jan Jakob Sonke, Cynthia L. Eccles, Robert E. Dinniwell, John Kim, Andrea Bezjak, Michael Milosevic, Kristy K. Brock, Laura A. Dawson pages 918-925 Abstract | Full Text | Full-Text PDF (575 KB)
Standard and Nonstandard Craniospinal Radiotherapy Using Helical TomoTherapy, 15 March 2010 William Parker, Marylene Brodeur, David Roberge, Carolyn Freeman pages 926-931 Abstract | Full Text | Full-Text PDF (1024 KB)
RapidArc Radiation Therapy: First Year Experience at the University of Alabama at Birmingham, 08 March 2010 Richard A. Popple, John B. Fiveash, Ivan A. Brezovich, James A. Bonner pages 932-941 Abstract | Full Text | Full-Text PDF (599 KB)
Volumetric Modulation Arc Radiotherapy Compared With Static Gantry Intensity-Modulated Radiotherapy for Malignant Pleural Mesothelioma Tumor: A Feasibility Study, 08 April 2010 Marta Scorsetti, Mario Bignardi, Alessandro Clivio, Luca Cozzi, Antonella Fogliata, Paola Lattuada, Pietro Mancosu, Piera Navarria, Giorgia Nicolini, Gaetano Urso, Eugenio Vanetti, Sabrina Vigorito, Armando Santoro pages 942-949 Abstract | Full Text | Full-Text PDF (824 KB)
Emphasizing Conformal Avoidance Versus Target Definition for IMRT Planning in Head-and-Neck Cancer, 07 April 2010 Paul M. Harari, Shiyu Song, Wolfgang A. Tomé pages 950-958 Abstract | Full Text | Full-Text PDF (5506 KB)
Evaluation of Automatic Atlas-Based Lymph Node Segmentation for Head-and-Neck Cancer, 15 March 2010 Liza J. Stapleford, Joshua D. Lawson, Charles Perkins, Scott Edelman, Lawrence Davis, Mark W. McDonald, Anthony Waller, Eduard Schreibmann, Tim Fox pages 959-966 Abstract | Full Text | Full-Text PDF (463 KB)
Other Content
Meetings page 967 Full Text | Full-Text PDF (48 KB)
ASTRO News page 968 Full Text | Full-Text PDF (42 KB)
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