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Introductory Papers
Guest Editor's Introduction to QUANTEC: A Users Guide Lawrence B. Marks, Randall K. Ten Haken, Mary K. Martel pages S1-S2 Full Text | Full-Text PDF (789 KB)
Quantitative Analyses of Normal Tissue Effects in the Clinic (QUANTEC): An Introduction to the Scientific Issues Søren M. Bentzen, Louis S. Constine, Joseph O. Deasy, Avi Eisbruch, Andrew Jackson, Lawrence B. Marks, Randall K. Ten Haken, Ellen D. Yorke pages S3-S9 Abstract | Full Text | Full-Text PDF (112 KB)
Use of Normal Tissue Complication Probability Models in the Clinic Lawrence B. Marks, Ellen D. Yorke, Andrew Jackson, Randall K. Ten Haken, Louis S. Constine, Avraham Eisbruch, Søren M. Bentzen, Jiho Nam, Joseph O. Deasy pages S10-S19 Abstract | Full Text | Full-Text PDF (484 KB)
Quantec: Organ-Specific Papers
Central Nervous System: Brain
Radiation Dose–Volume Effects in the Brain Yaacov Richard Lawrence, X. Allen Li, Issam el Naqa, Carol A. Hahn, Lawrence B. Marks, Thomas E. Merchant, Adam P. Dicker pages S20-S27 Abstract | Full Text | Full-Text PDF (401 KB)
Central Nervous System: Optic Nerve/Chaism
Radiation Dose–Volume Effects of Optic Nerves and Chiasm Charles Mayo, Mary K. Martel, Lawrence B. Marks, John Flickinger, Jiho Nam, John Kirkpatrick pages S28-S35 Abstract | Full Text | Full-Text PDF (196 KB)
Central Nervous System: Brain Stem
Radiation Associated Brainstem Injury Charles Mayo, Ellen Yorke, Thomas E. Merchant pages S36-S41 Abstract | Full Text | Full-Text PDF (159 KB)
Central Nervous System: Spinal Cord
Radiation Dose–Volume Effects in the Spinal Cord John P. Kirkpatrick, Albert J. van der Kogel, Timothy E. Schultheiss pages S42-S49 Abstract | Full Text | Full-Text PDF (188 KB)
Central Nervous System:Ear
Radiation Therapy and Hearing Loss Niranjan Bhandare, Andrew Jackson, Avraham Eisbruch, Charlie C. Pan, John C. Flickinger, Patrick Antonelli, William M. Mendenhall pages S50-S57 Abstract | Full Text | Full-Text PDF (419 KB)
Head and Neck: Parotoid
Radiotherapy Dose–Volume Effects on Salivary Gland Function Joseph O. Deasy, Vitali Moiseenko, Lawrence Marks, K.S. Clifford Chao, Jiho Nam, Avraham Eisbruch pages S58-S63 Abstract | Full Text | Full-Text PDF (280 KB)
Head and Neck: Larynx/Pharynx
Radiation Dose–Volume Effects in the Larynx and Pharynx Tiziana Rancati, Marco Schwarz, Aaron M. Allen, Felix Feng, Aron Popovtzer, Bharat Mittal, Avraham Eisbruch pages S64-S69 Abstract | Full Text | Full-Text PDF (147 KB)
Thorax: Lung
Radiation Dose–Volume Effects in the Lung Lawrence B. Marks, Soren M. Bentzen, Joseph O. Deasy, Feng-Ming (Spring) Kong, Jeffrey D. Bradley, Ivan S. Vogelius, Issam El Naqa, Jessica L. Hubbs, Joos V. Lebesque, Robert D. Timmerman, Mary K. Martel, Andrew Jackson pages S70-S76 Abstract | Full Text | Full-Text PDF (413 KB)
Thorax: Heart
Radiation Dose–Volume Effects in the Heart Giovanna Gagliardi, Louis S. Constine, Vitali Moiseenko, Candace Correa, Lori J. Pierce, Aaron M. Allen, Lawrence B. Marks pages S77-S85 Abstract | Full Text | Full-Text PDF (223 KB)
Thorax: Esophagus
Radiation Dose-Volume Effects in the Esophagus Maria Werner-Wasik, Ellen Yorke, Joseph Deasy, Jiho Nam, Lawrence B. Marks pages S86-S93 Abstract | Full Text | Full-Text PDF (216 KB)
Abdomen: Liver
Radiation-Associated Liver Injury Charlie C. Pan, Brian D. Kavanagh, Laura A. Dawson, X. Allen Li, Shiva K. Das, Moyed Miften, Randall K. Ten Haken pages S94-S100 Abstract | Full Text | Full-Text PDF (318 KB)
Abdomen: Stomach/Small Bowel
Radiation Dose–Volume Effects in the Stomach and Small Bowel Brian D. Kavanagh, Charlie C. Pan, Laura A. Dawson, Shiva K. Das, X. Allen Li, Randall K. Ten Haken, Moyed Miften pages S101-S107 Abstract | Full Text | Full-Text PDF (173 KB)
Abdomen: Kidney
Radiation-Associated Kidney Injury Laura A. Dawson, Brian D. Kavanagh, Arnold C. Paulino, Shiva K. Das, Moyed Miften, X. Allen Li, Charlie Pan, Randall K. Ten Haken, Timothy E. Schultheiss pages S108-S115 Abstract | Full Text | Full-Text PDF (309 KB)
Pelvis: Bladder
Radiation Dose–Volume Effects of the Urinary Bladder Akila N. Viswanathan, Ellen D. Yorke, Lawrence B. Marks, Patricia J. Eifel, William U. Shipley pages S116-S122 Abstract | Full Text | Full-Text PDF (160 KB)
Pelvis: Rectum
Radiation Dose–Volume Effects in Radiation-Induced Rectal Injury Jeff M. Michalski, Hiram Gay, Andrew Jackson, Susan L. Tucker, Joseph O. Deasy pages S123-S129 Abstract | Full Text | Full-Text PDF (166 KB)
Pelvis: Penile Bulb
Radiation Dose–Volume Effects and the Penile Bulb Mack Roach, Jiho Nam, Giovanna Gagliardi, Issam El Naqa, Joseph O. Deasy, Lawrence B. Marks pages S130-S134 Abstract | Full Text | Full-Text PDF (951 KB)
Vision Papers
Accurate Accumulation of Dose for Improved Understanding of Radiation Effects in Normal Tissue David A. Jaffray, Patricia E. Lindsay, Kristy K. Brock, Joseph O. Deasy, W.A. Tomé pages S135-S139 Abstract | Full Text | Full-Text PDF (95 KB)
Imaging for Assessment of Radiation-Induced Normal Tissue Effects Robert Jeraj, Yue Cao, Randall K. Ten Haken, Carol Hahn, Lawrence Marks pages S140-S144 Abstract | Full Text | Full-Text PDF (141 KB)
Biomarkers and Surrogate Endpoints for Normal-Tissue Effects of Radiation Therapy: The Importance of Dose–Volume Effects Søren M. Bentzen, Matthew Parliament, Joseph O. Deasy, Adam Dicker, Walter J. Curran, Jacqueline P. Williams, Barry S. Rosenstein pages S145-S150 Abstract | Full Text | Full-Text PDF (110 KB)
Improving Normal Tissue Complication Probability Models: The Need to Adopt a “Data-Pooling” Culture Joseph O. Deasy, Søren M. Bentzen, Andrew Jackson, Randall K. Ten Haken, Ellen D. Yorke, Louis S. Constine, Ashish Sharma, Lawrence B. Marks pages S151-S154 Abstract | Full Text | Full-Text PDF (193 KB)
The Lessons of QUANTEC: Recommendations for Reporting and Gathering Data on Dose–Volume Dependencies of Treatment Outcome Andrew Jackson, Lawrence B. Marks, Søren M. Bentzen, Avraham Eisbruch, Ellen D. Yorke, Randal K. Ten Haken, Louis S. Constine, Joseph O. Deasy pages S155-S160 Abstract | Full Text | Full-Text PDF (105 KB)
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