Current Issue 1 March 2012, Vol. 82, No. 3
Full Table of ContentsA Warm Welcome to Dr. Zietman
With the January 2012 issue, Anthony L. Zietman, MD, FASTRO, begins his term as Editor-in-Chief of the Red Journal, taking up the reins from James Cox. Elsevier and ASTRO welcome Dr. Zietman to the Journal and look forward to its continued success under his leadership.
Read ASTRO press release.
Read Dr. Zietman's editorial from the January issue.
Read Dr. Wilson's tribute to Dr. Cox.
CME Article
- Radiotherapy for Liver Metastases: A Review of Evidence
Morten Høyer, Anand Swaminath, Sean Bydder, Michael Lock, Alejandra Méndez Romero, Brian Kavanagh, Karyn A. Goodman, Paul Okunieff, Laura A. Dawson
Issue Highlights
- Validating the RTOG-Endorsed Brachial Plexus Contouring Atlas: An Evaluation of Reproducibility Among Patients Treated by Intensity-Modulated Radiotherapy for Head-and-Neck Cancer
In this study the Radiation Therapy Oncology Group-endorsed brachial plexus contouring atlas was used to guide three radiation oncologists to independently delineate this particular structure on treatment planning CT scans from representative head-and-neck cancer patients undergoing IMRT. Inter-observer differences were remarkably small and thus this atlas appears to provide a consistent set of guidelines for contouring with essentially no learning curve.
- Effects of Irradiation on Brain Vasculature Using an In Situ Tumor Model
The authors tested the hypothesis that the presence of tumor alters the response of normal tissues to irradiation using a novel in situ rat brain tumor model. Studying several different vascular endpoints they found that the presence of tumor alone increases peri-tumoral vessel permeability and, following radiation, reduces the presence of VEGF in adjacent normal tissue. This model represents a useful system to evaluate the interaction between tumor and brain after radiation treatment.
- Curative Treatment of Stage I Non-Small-Cell Lung Cancer in Patients With Severe COPD: Stereotactic Radiotherapy Outcomes and Systematic Review
Palma et al. studied outcomes after stereotactic body radiotherapy (SBRT) for stage I non-small-cell lung cancer in patients with severe COPD and made comparison with published surgical series. In this single-institution cohort, actuarial 3-year local control was 89%, and 1- and 3-year overall survival were 79% and 47%, respectively. COPD severity correlated with survival. High control rates in these patients were achieved without the approximately 10% 30-day mortality seen in surgical series.
- Basal Subtype of Invasive Breast Cancer is Associated With a Higher Risk of True Recurrence After Conventional Breast-Conserving Therapy
This study utilized a large single-institution database to determine whether or not a correlation existed between breast cancer subtype and patterns of ipsilateral breast tumor recurrence (true vs. elsewhere) among women with pT1–T2 invasive breast cancer receiving breast-conserving therapy. Basal and HER-2 subtypes were significantly associated with higher rates of true recurrence arguing that additional strategies such as increased boost doses, concomitant radiation and chemotherapy, or targeted therapy agents, deserve exploration.
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In Vivo Dosimetry for Single-Fraction Targeted Intraoperative Radiotherapy (TARGIT) for Breast Cancer01 February 2012
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Critical Appraisal of Acuros XB and Anisotropic Analytic Algorithm Dose Calculation in Advanced Non-Small-Cell Lung Cancer Treatments01 February 2012
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Decreased Risk of Radiation Pneumonitis with Incidental Concurrent Use of Angiotensin-Converting Enzyme Inhibitors and Thoracic Radiation Therapy01 February 2012
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MRI-based Preplanning Using CT and MRI Data Fusion in Patients with Cervical Cancer Treated with 3D-based Brachytherapy: Feasibility and Accuracy Study01 February 2012
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Quality Assurance of Multifractionated Pelvic Interstitial Brachytherapy for Postoperative Recurrences of Cervical Cancers: A Prospective Study01 February 2012
Effect of Image-Guidance Frequency on Geometric Accuracy and Setup Margins in Radiotherapy for Locally Advanced Lung Cancer
