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Radiotherapy & Oncology
Volume 92, Issue 3, Pages 293-510 (September 2009)
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Special Issue on Molecular and Experimental Radiobiology Including papers from the 11th International Wolfsberg Meeting on Molecular Radiation Biology/Oncology

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Editorial Board
page iv
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Contents
pages vii-viii
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Editorial


Molecular radiation biology: Perspectives for radiation oncology, 02 September 2009
H. Peter Rodemann
pages 293-298
Full Text | Full-Text PDF (164 KB)

Systematic review


Genetic variants and normal tissue toxicity after radiotherapy: A systematic review, 17 August 2009
Christian Nicolaj Andreassen, Jan Alsner
pages 299-309
Abstract | Full Text | Full-Text PDF (588 KB)

Reviews


Backup pathways of NHEJ in cells of higher eukaryotes: Cell cycle dependence, 15 July 2009
George Iliakis
pages 310-315
Abstract | Full Text | Full-Text PDF (433 KB)


Receptor signaling as a regulatory mechanism of DNA repair, 17 July 2009
Raymond E. Meyn, Anapama Munshi, John V. Haymach, Luka Milas, K. Kian Ang
pages 316-322
Abstract | Full Text | Full-Text PDF (334 KB)


Promotion of autophagy as a mechanism for radiation sensitization of breast tumor cells, 22 June 2009
David A. Gewirtz, Molly L. Hilliker, Eden N. Wilson
pages 323-328
Abstract | Full Text | Full-Text PDF (203 KB)


Pyruvate into lactate and back: From the Warburg effect to symbiotic energy fuel exchange in cancer cells, 15 July 2009
Olivier Feron
pages 329-333
Abstract | Full Text | Full-Text PDF (329 KB)

Original articles


2-Methoxyestradiol-induced radiosensitization is independent of SOD but depends on inhibition of Akt and DNA-PKcs activities, 09 July 2009
Urszula Florczak, Mahmoud Toulany, Rainer Kehlbach, H. Peter Rodemann
pages 334-338
Abstract | Full Text | Full-Text PDF (486 KB)


Inhibition of STAT-3 results in radiosensitization of human squamous cell carcinoma, 21 July 2009
James A. Bonner, Hoa Q. Trummell, Christopher D. Willey, Brian A. Plants, Kevin P. Raisch
pages 339-344
Abstract | Full Text | Full-Text PDF (457 KB)


Expression of the bifunctional suicide gene CDUPRT increases radiosensitization and bystander effect of 5-FC in prostate cancer cells, 12 May 2009
Ligang Xing, Xiaorong Sun, Xuelong Deng, Khushali Kotedia, Muneyasu Urano, Jason A. Koutcher, C. Clifton Ling, Gloria C. Li
pages 345-352
Abstract | Full Text | Full-Text PDF (1329 KB)


CD133 expression is not selective for tumor-initiating or radioresistant cell populations in the CRC cell lines HCT-116, 25 August 2009
Claudia Dittfeld, Antje Dietrich, Susann Peickert, Sandra Hering, Michael Baumann, Marian Grade, Thomas Ried, Leoni A. Kunz-Schughart
pages 353-361
Abstract | Full Text | Full-Text PDF (792 KB)


Caveolin-1 mediated radioresistance of 3D grown pancreatic cancer cells, 10 August 2009
Stephanie Hehlgans, Iris Eke, Katja Storch, Michael Haase, Gustavo B. Baretton, Nils Cordes
pages 362-370
Abstract | Full Text | Full-Text PDF (783 KB) | Add-Ons


3D cell cultures of human head and neck squamous cell carcinoma cells are radiosensitized by the focal adhesion kinase inhibitor TAE226, 03 September 2009
Stephanie Hehlgans, Inga Lange, Iris Eke, Nils Cordes
pages 371-378
Abstract | Full Text | Full-Text PDF (1570 KB)


Radiation-induced lipid peroxidation activates src kinase and triggers nuclear EGFR transport, 29 June 2009
Klaus Dittmann, Claus Mayer, Rainer Kehlbach, Marie-Christine Rothmund, H. Peter Rodemann
pages 379-382
Abstract | Full Text | Full-Text PDF (283 KB)


Enhanced response to C225 of A431 tumor xenografts growing in irradiated tumor bed, 20 August 2009
Oliver Riesterer, Kathryn A. Mason, Uma Raju, Qiuan Yang, Li Wang, Walter N. Hittelman, K. Kian Ang, Luka Milas
pages 383-387
Abstract | Full Text | Full-Text PDF (366 KB)


Concurrent cetuximab, cisplatin, and radiation for squamous cell carcinoma of the head and neck in vitro, 18 May 2009
Na Zhang, Kaisa Erjala, Jarmo Kulmala, Xueshan Qiu, Maria Sundvall, Klaus Elenius, Reidar Grénman
pages 388-392
Abstract | Full Text | Full-Text PDF (275 KB)


Binding of cetuximab to the EGFRvIII deletion mutant and its biological consequences in malignant glioma cells, 21 July 2009
Barry Jutten, Ludwig Dubois, Younan Li, Hugo Aerts, Bradly G. Wouters, Philippe Lambin, Jan Theys, Guido Lammering
pages 393-398
Abstract | Full Text | Full-Text PDF (442 KB)


The deletion mutant EGFRvIII significantly contributes to stress resistance typical for the tumour microenvironment, 21 July 2009
Jan Theys, Barry Jutten, Ludwig Dubois, Kasper M.A. Rouschop, Roland K. Chiu, Younan Li, Kim Paesmans, Philippe Lambin, Guido Lammering, Bradly G. Wouters
pages 399-404
Abstract | Full Text | Full-Text PDF (562 KB)


Triple angiokinase inhibition, tumour hypoxia and radiation response of FaDu human squamous cell carcinomas, 01 May 2009
Daniel Zips, Katja Le, Ala Yaromina, Annegret Dörfler, Wolfgang Eicheler, Xuanjing Zhou, Peter Geyer, Frank Hilberg, Michael Baumann
pages 405-410
Abstract | Full Text | Full-Text PDF (290 KB)


Autophagy is required during cycling hypoxia to lower production of reactive oxygen species, 21 July 2009
Kasper M.A. Rouschop, Chantal H.M.A. Ramaekers, Marco B.E. Schaaf, Tom G.H. Keulers, Kim G.M. Savelkouls, Philippe Lambin, Marianne Koritzinsky, Bradly G. Wouters
pages 411-416
Abstract | Full Text | Full-Text PDF (471 KB)


The use of a comprehensive tumour xenograft dataset to validate gene signatures relevant for radiation response, 17 July 2009
Maud H.W. Starmans, Daniel Zips, Bradly G. Wouters, Michael Baumann, Philippe Lambin
pages 417-422
Abstract | Full Text | Full-Text PDF (331 KB)


Imaging of CA IX with fluorescent labelled sulfonamides distinguishes hypoxic and (re)-oxygenated cells in a xenograft tumour model, 21 July 2009
Ludwig Dubois, Natasja G. Lieuwes, Alfonso Maresca, Anne Thiry, Claudiu T. Supuran, Andrea Scozzafava, Bradly G. Wouters, Philippe Lambin
pages 423-428
Abstract | Full Text | Full-Text PDF (473 KB)


Can hypoxia-PET map hypoxic cell density heterogeneity accurately in an animal tumor model at a clinically obtainable image contrast?, 03 September 2009
Morten Busk, Michael R. Horsman, Steen Jakobsen, Kim V. Hansen, Johan Bussink, Albert van der Kogel, Jens Overgaard
pages 429-436
Abstract | Full Text | Full-Text PDF (553 KB)


Deficient carbonic anhydrase 9 expression in UPR-impaired cells is associated with reduced survival in an acidic microenvironment, 17 July 2009
Twan van den Beucken, Chantal H.M.A. Ramaekers, Kasper Rouschop, Marianne Koritzinsky, Bradly G. Wouters
pages 437-442
Abstract | Full Text | Full-Text PDF (392 KB)


Proteins upregulated by mild and severe hypoxia in squamous cell carcinomas in vitro identified by proteomics, 22 June 2009
Brita Singers Sørensen, Michael R. Horsman, Henrik Vorum, Bent Honoré, Jens Overgaard, Jan Alsner
pages 443-449
Abstract | Full Text | Full-Text PDF (1284 KB)


Hypoxic activation of the unfolded protein response (UPR) induces expression of the metastasis-associated gene LAMP3, 02 September 2009
Hilda Mujcic, Tomasz Rzymski, Kasper M.A. Rouschop, Marianne Koritzinsky, Manuela Milani, Adrian L. Harris, Bradly G. Wouters
pages 450-459
Abstract | Full Text | Full-Text PDF (721 KB)


Core needle biopsies for determination of the microenvironment in individual tumours for longitudinal radiobiological studies, 17 August 2009
Ala Yaromina, Anja Eckardt, Daniel Zips, Wolfgang Eicheler, Christina Schuetze, Howard Thames, Michael Baumann
pages 460-465
Abstract | Full Text | Full-Text PDF (692 KB)


Isolation and characterization of human salivary gland cells for stem cell transplantation to reduce radiation-induced hyposalivation, 22 July 2009
Jielin Feng, Marianne van der Zwaag, Monique A. Stokman, Ronald van Os, Robert P. Coppes
pages 466-471
Abstract | Full Text | Full-Text PDF (541 KB)


Effect of selective inhibitors of inflammation on oral mucositis: Preclinical studies, 03 July 2009
Julia Haagen, Hanna Krohn, Sophie Röllig, Margret Schmidt, Kathrin Wolfram, Wolfgang Dörr
pages 472-476
Abstract | Full Text | Full-Text PDF (148 KB)


Novel insights into pathological changes in muscular arteries of radiotherapy patients, 22 June 2009
Nicola S. Russell, Saske Hoving, Sylvia Heeneman, J. Joris Hage, Leonie A.E. Woerdeman, Remco de Bree, Peter J.F.M. Lohuis, Ludi Smeele, Jack Cleutjens, Addy Valenkamp, Lucille D.A. Dorresteijn, Otilia Dalesio, Mat J. Daemen, Fiona A. Stewart
pages 477-483
Abstract | Full Text | Full-Text PDF (471 KB)


Endoglin haploinsufficiency reduces radiation-induced fibrosis and telangiectasia formation in mouse kidneys, 03 July 2009
Marion Scharpfenecker, Ben Floot, Nicola S. Russell, Peter ten Dijke, Fiona A. Stewart
pages 484-491
Abstract | Full Text | Full-Text PDF (799 KB)


Lovastatin attenuates ionizing radiation-induced normal tissue damage in vivo, 17 July 2009
Christian Ostrau, Johannes Hülsenbeck, Melanie Herzog, Arno Schad, Michael Torzewski, Karl J. Lackner, Gerhard Fritz
pages 492-499
Abstract | Full Text | Full-Text PDF (667 KB)


Effects of genistein following fractionated lung irradiation in mice, 12 May 2009
Andrea E. Para, Andrea Bezjak, Ivan W.T. Yeung, Jake Van Dyk, Richard P. Hill
pages 500-510
Abstract | Full Text | Full-Text PDF (1213 KB)


Important ESTRO dates
page I
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